Banca de DEFESA: JANIA DOS SANTOS ROSARIO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : JANIA DOS SANTOS ROSARIO
DATA : 25/03/2020
HORA: 14:00
LOCAL: auditório campus VI
TÍTULO:

Synthesis and characterization of gallium (III) and bismuth (III) complexes beraring bioactive ligands


PALAVRAS-CHAVES:

Bismuth (III), gallium (III), anticancer, antibacterial, ciprofloxacin, hydroxyquinoline


PÁGINAS: 60
GRANDE ÁREA: Ciências Exatas e da Terra
ÁREA: Química
SUBÁREA: Química Inorgânica
ESPECIALIDADE: Química Bio-Inorgânica
RESUMO:

Nowadays there has been an expansion of gallium and bismuth compounds with therapeutic potential. Gallium (III) is able to mimic iron(III) by replacing it at various iron-dependent sites, causing disruption of cell replication, which is an important mechanism against tumor cell proliferation. Bismuth(III), in turn, has been used to treat gastrointestinal disorders, ulcers and bacterial infections, especially those caused by the bacterium Helicobacter pylori. Bismuth has the great advantage of low cytotoxicity. Thus, this work consists of combining the pharmacological properties of these metallic ions with bioactive ligands.


MEMBROS DA BANCA:
Presidente - PRISCILA PEREIRA SILVA CALDEIRA
Interno - EUDES LORENCON
Externo à Instituição - WILLIAN XERXES COELHO OLIVEIRA - UFMG
Notícia cadastrada em: 04/03/2020 13:45
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